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J., Azimifar, S

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AKB-6548, a novel hypoxia-inducible factor prolyl hydroxylase inhibitor reduces hepcidin and ferritin while it increases reticulocyte production and total iron binding capacity in healthy adults [abstract]

As demonstrated, introduction of the QMP substitutions resulted in a favorable receptor binding, efficient FcRn-mediated cellular recycling, and consequently, extended plasma half-life both in the unfused albumin and GLP-1 albumin fusion formats

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