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Reactive metabolites from lipid peroxidation disrupt essential cellular structures, initiating cell death and DAMP releasea process further amplified by antioxidant depletion and exemplified in SLE, where neutrophils undergo ferroptosis and NETosis, activating TLR-dependent ROS generation that propagates inflammatory tissue injury (76, 87, 113115)

10.1038/s41392-020-0116-z 43

doi:10.1093/carcin/23.10.1721

Prevalence of autoantibody responses in acute coronavirus disease 2019 (COVID-19)

Identification of an ancillary protein, YabF, required for activity of the KefC glutathione-gated potassium efflux system in Escherichia coli

In an HFD-induced steatosis model, this supplementation effectively suppressed elevations in the pro-inflammatory cytokines TNF- and IL-6, an effect not achieved by either intervention alone