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This specificity strengthens the potential of G1 as a targeted modulator

In the initial phase of tumor growth, oxygen supply is not a limiting factor for mutant cell survival because of easy access to pO2 from nearby vasculature

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Mouse Nrf2, Kelch-like ECH-associated protein 1 (Keap1), and NAD(P)H:quinone oxidoreductase 1 (NQO1) ELISA kits were purchased from CUSABIO (Wuhan, China)