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Reported activators of GPX4, such as 1d4, SeMet, and CDDO, or inhibitors of GPX4 degradation are promising for pain relief, which may be related to the inhibition of inflammation and oxidative stress

The cells treated with Sp showed slight enhancement in levels of GSH (~1.2 fold), together with minor alterations in GSSG levels, compared to untreated samples which exhibited higher GSSG content, thus indicating efficient recycling of GSSG to GSH (Fig

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In: Nitric oxide and hydrogen peroxide signalling in higher plants

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