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93 After using guinea pig asparaginase 1 (gpASNase1) to promote the conversion of Asn to Asp in tumor cells, the growth rate of tumor cells was significantly increased, suggesting that Asp acquisition is an endogenous metabolic limitation in tumors with difficult Asp acquisition

CA: A Cancer J Clinicians

In addition, GSTP1 can mediate the S-glutathionylation of some proteins and interact with them [56] such as Keap1 [57] and PKM2 [58]

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Although deficiency of 6PGD is well documented, it appears to have little or no significance for red cell viability

& Boya, P