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Macrophages, particularly the M2 subtype, play a key role in calcific aortic stenosis, and their expression of the pattern recognition receptor Toll-like receptor 7 (TLR7) is associated with inflammation and calcification processes in the aortic valve (265)

Various studies have reported that ISO-treatment mimics clinical MI that induces TNF- and IL-6 activation thus contributing to inflammation in response to myocardial injury ( Over the past decade, several synthetic drugs have been developed for treatment of the cardiovascular disorders

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

Plant Physiol 165(2):519527

Weve already mentioned that MS is a complex, autoimmune disease

TRPV1 activation improves exercise endurance and energy metabolism through PGC-1 upregulation in mice