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& Fleming, T

W., Combs, T

Novel bispecific nanobody mitigates experimental intestinal inflammation in mice by targeting TNF-alpha and IL-23p19 bioactivities

Gastroenterology 165 , 682695 (2023)

Although the heterologeous expression of an insect steroid receptor in CHO-K1 cells differs largely from the situation found in LNCaP cells that express high levels of intracellular AR under physiological conditions the present data suggest that there are cell specific differences in the sensitivity of cells towards NO-treatment

This is why insulin, growth hormone, and many other peptide-based medications require injection-oral administration would result in degradation before the compound reaches systemic circulation