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Doctors and scientists are calling for rigorous human studies to determine the long-term safety of the Wolverine Stack

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Adequate intake of B vitamins is required for healthy homocysteine levels, translating into better brain health

Rather than relying on self-reported dietary compliance, any evaluation of clinical efficacy should be correlated with measurements of blood glucose and blood ketones (which can then be used to derive the GKI), as well other objective biological measurements (e.g., insulin, metabolic imaging, metabolomics), allowing for inter-study comparisons and external validity under different methodologies [102, 134, 145, 175]