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Key finding: AOD 9604 increased type II collagen synthesis by 180% and cartilage proteoglycan content by 156% in human OA chondrocytes

Stress-induced hyperactivation of the HPA axis leads to elevated cortisol levels that disrupt normal sleep architecture

J Am Chem Soc 127(18):65166517 Lux B, May P (1938) Long-term observation of young cystinuric patients under ascorbic acid therapy

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In comparison, the stable gastric pentadecapeptide BPC 157, an emerging treatment with potential therapeutic applications, appears to be unrestricted by the limitations seen in previous therapies