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Valoti, Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis, Biochemical pharmacology 71(10) (2006) 1510-1519

doi: 10.3390/antiox12091721

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While the Fe-S cluster is critical for activity, its role for the reaction mechanism remains unclear ( in vitro using glutathione disulfide (GSSG) or in vivo in response to ozone and paraquat, and inactivated upon reduction ( Four APK proteins exist in Arabidopsis, APK1, 2, and 4 locate in plastids whereas APK3 is in the cytosol (Mugford et al., 2009)

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After 4 weeks: The dosage should be increased to 5 mg subcutaneously once a week