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For instance, in AD mice, mitochondrial damage increases mtDNA leakage into the cytosol, where it engages cGAS and activates STING, driving microglial secretion of type I interferons and pro-inflammatory cytokines that contribute to neuronal dysfunction [93]

Notably, postnatal use up to 18 months was not associated with these outcomes

Furthermore, rats that received curcumin showed reduced levels of pro-inflammatory cytokines IL-6 and IFN

(2004) reported that vitamin D supplementation in the first year of life was associated with a 77% decrease in the incidence of schizophrenia

Orlowski JP, Hanhan UA, Fiallos MR