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A Nature Scientific Reports 2016 study showed GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 M over 72 hours and did NOT induce inflammatory biomarkers (IL-1, IL-8, HSPA1A, FOSL1) unlike other copper compounds, concluding GHK-Cu has a low potential of inducing skin irritation

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Moreover, the experimental data on cognitive improving effect of noopept have been confirmed in clinic (Phase III and postregistration trials) demonstrating beneficial effect on cognitive functions in patients with MCI of cerebro-vascular or posttraumatic origin [21], and in particular in patients with amnestic form of MCI carrying APOE 4 + allele [22]

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This structure gives GHK-Cu a characteristic blue hue in solution, with an absorption peak at 610630 nm

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