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The average diet supplies about 5 to 15 mcg/day of vitamin B 12in a protein-bound form that is available for absorption after normal digestion

The compound remains in a regulatory gray area: recognized as safe, but without the efficacy data needed for pharmaceutical approval

Once denatured, the peptide cannot refold correctly

Furthermore, Vit B12 status is more likely to present a potential determinant factor of developing PD

In an era where a variety of different therapeutic options is the norm for the management of chronic diseases such as type 2 diabetes and hypertension, the hope is that this process will led to better personalized anti-obesity treatments, focusing on the special characteristics, needs, and comorbidities of each patient and the effectiveness and safety of the recommended therapy