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Caspase-1 is a key effector protein of NLRP3

Exposure of A2e to blue light promotes ferroptosis in the retinal pigment epithelium

All mice were housed in a specific pathogen-free environment at a constant temperature (25 C 1 C) and 50% to 60% relative humidity

The number of viable cells was measured by flow cytometry after addition of 5 l spike in fluorescently labeled bead (CountBright Plus Absolute Counting Beads, ThermoFisher Scientific) for normalization