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Published online February 21, 2020 DOI: 22,014 View 322 Download 102 Web of Science 105 Crossref Abstract PDFPubReader ePub Mitochondrial medicine is increasingly discussed as a promising therapeutic approach, given that mitochondrial defects are thought to contribute to many prevalent diseases and their complications

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Oxidation of methionine can generate two diastereomeres that are reduced by two different non-related enzyme families, namely MSRA (reducing methionine- S -sulfoxide) and MSRB (reducing methionine- R -sulfoxide) [52]

In antioxidant defence, glutathione is very important because it helps cells deal with oxidative stress and keep their internal environment stable

Thus, ascorbate reductases like MDHARs, which are responsible for the reduction of AsA have considerable roles in stress tolerance

Juices in the stomach break the GSH molecule into its three constituting amino acids glutamate, L-cysteine, and glycine which must then be reassembled into GSH