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A significant proportion of the published work comes from a single research group the Zagreb laboratory associated with Sikiric and colleagues

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Common causes of B12 deficiency include poor dietary intake, certain medical conditions (such as pernicious anemia or gastrointestinal disorders), and the bodys decreased ability to absorb B12 with age

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Aliquot and store at 80 C after reconstitution to avoid freeze-thaw degradation

The sterile, preservative-containing solution dissolves powdered compounds cleanly without introducing contaminants, preserving the integrity of the reconstituted solution across multiple uses