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2 ALS Genetics While only a minority of patients with ALS harbor a monogenic cause, the downstream consequences of genetic mutations in patients with ALS have improved mechanistic insights

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The clinic also notes that MGF is used in cycles aligned with training programmes

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Further studies focusing on elucidating the structural basis of the autophagy interaction for pyroptosis induction and developing autophagy-related drugs need to be explored in clinical trials (Figure 4)

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