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Shu et al., PNAS 90:7995-7999 (1993)

Selenium is generally taken up from the diet through food or other forms of external supplementation

Alharby, B

2021 Jul;27(5):1148-1160

290 Furthermore, the selective FGFR inhibitor PD173074 alone also resulted in a remarkable response in an HNSCC xenograft model

We hypothesize that reduced CPT-I activity may contribute to persistent fatigue in these congenital hypothyroid patients, even after levothyroxine therapy, which alone may be insufficient to fully address the downstream metabolic consequences of TPO and TSHR gene mutations present in this cohort