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Karege F, Vaudan G, Schwald M, Perroud N, La Harpe R

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Attaai, A

Inflammation research represents another major application area

Most protocols recommend evening injections , typically 1-2 hours before intended sleep time

549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons