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Description

Glutathione deficiency caused inflammation in mice

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In addition GSNO knockout mice exhibit an increase in lung S-nitrosothiols and are protected from allogen-induced airway hyperresponsivity.[76]

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This is consistent with TPP-IAM-based alkylation of PrSH as well as of PrSS and PrS(S) n S terminal sulfur atoms

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S.GamellC.MeggyesyP

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Li, T., Xu, Z

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The classical paradigm classifies macrophages into pro-inflammatory M1 and anti-inflammatory/reparative M2 phenotypes (18-20)

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