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Stojakovic A, Trushin S, Sheu A et al (2021) Partial inhibition of mitochondrial complex I ameliorates Alzheimers disease pathology and cognition in APP/PS1 female mice

CPZ ( bis -cyclohexanoneoxalyhydrazone) is a well-established demyelinating toxicant, inducing consistent and widespread demyelination in vivo following 6 weeks of daily 0.20.3% CPZ treatment that can be reversed by endogenous remyelination occurring on cessation of treatment (Blakemore, 1972