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For these regions, the side chains were stubbed in the final PDB models if no robust density was present in the EM maps

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Cu ions directly bind to the lipoyl groups, inducing aberrant oligomerization of DLAT and other TCA cycle enzymes, promoting the loss of Fe-S cluster proteins

172 Each of these aspects can influence the mechanical properties of the ACL and its ability to withstand the stresses encountered during physical activities, making them critical considerations in both the prevention and rehabilitation of ACL injuries (Table 4.)

In contrast, IBD causes chronic inflammation that can lead to long-term tissue injury if untreated

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