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Furthermore, analyzing these possible biomarkers in the tongue at different ages can help to understand the protection mechanisms involved in the pathological process and support the development of future approaches for the diagnosis and monitoring progression of DMD

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While this model does not have an obvious way to couple E2F-dependent expression of cyclins E and A to cell growth, this could be provided by growth diluting Rb in G1 18,19

The administration of PTU to the animal model indicated acute hypothyroidism and acute physiological stress

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