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Expecting a median follow-up of at least 12 months (12 periods of 4 weeks), a total number of at least 90 patients (60 in EBS group and 30 in ABS group) were required

Alzheimers Res Ther 6:18 Nygaard HB, Wagner AF, Bowen GS, Good SP, MacAvoy MG, Strittmatter KA, Kaufman AC, Rosenberg BJ, Sekine-Konno T, Varma P, Chen K (2015) A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimers disease

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Adequate hydration is also essential to prevent nephrotoxicity by maintaining adequate renal perfusion and enhancing drug clearance

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10.1016/S0304-4165(01)00235-5 10 AsadaK