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This causes the release of cyt c into the cell cytoplasm, which then activates a caspase cascade, particularly caspase-3 and caspase-9, resulting in mitochondrial impairment and triggering apoptosis (Yao et al., 2021)

Like other antiepileptic drugs, valproic acid may cause suicidal thoughts or actions in a very small number of people, about 1 in 500

(PubMed) da Costa KA, Kozyreva OG, Song J, Galanko JA, Fischer LM, Zeisel SH

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