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J Clin Endocrinol Metab 100:636643 Courchesne-Loyer A, Croteau E, Castellano C-A, St-Pierre V, Hennebelle M, Cunnane SC (2016) Inverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: a dual tracer quantitative positron emission tomography study

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Older age is a risk factor, as pernicious anemia is more common in individuals over 60