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These inconsistencies suggest translational gaps between experimental models and patient outcomes

Figure 5 reproduces the right panel of Figure 4 and shows what would happen if the activation of AS3MT by GSH or the sequestration of arsenicals by GSH is eliminated

DON treatment activates AMPK in cancer cells by increasing the AMP/ATP ratio and decreasing the expression of c-Myc proteins, thereby inhibiting glycolytic metabolism and suppressing cancer cell growth in vitro 145

[37] used carnitine-conjugated nanoparticles targeting OCTN2 and ATB 0,+ to deliver chemotherapeutic agents to colon cancer

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CDDO-Me was used at a concentration of 3 mg/kg, DKFZ-682 at 4 mg/kg and 10 mg/kg alone and in combination with CDDO-Me, respectively