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Our findings uncover an inflammatory, metabolically reprogrammed eosinophil population that promotes chronic skin inflammation by limiting protective T cell responses

Individuals with reduced activity of the DHFR enzyme, which is responsible for the first step in folic acid metabolism, may be less able to convert folic acid efficiently

Emerging cellular therapies for cancer

Metabolic syndrome and male fertility

Uricase nanocapsules extend the catalytic activity cycle of the enzyme, converting uric acid into readily excretable allantoin, whereas allopurinol nanoformulations enhance the inhibition of uric acid synthesis and the prevention of kidney stones through targeted delivery (Kandav et al., 2020