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Alpha-1 Antitrypsin Deficiency (AATD-1) Beam Therapeutics is testing a base editing treatment for alpha-1 antitrypsin deficiency (AATD-1)

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Cysteine is taken up by cells via the Glutamate/Cystine transporter xCT (SLC7A11), which has been found overexpressed in several cancers and is responsible for a novel way of cell death called ferroptosis (77)