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Funding This study was supported by the National Natural Science Foundation of China (32160255)

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At the collection type level, each measure will be assigned points based upon the current benchmarking data: new measures receive 7 or 5 points based on year in the program, measures with benchmarks are given points based upon the highest decile achievable with a less than perfect score (less than 100 ( percent or greater than 0 percent for inverse measures), and measures with no available historic benchmark are given 0 points

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Because 5-amino-1MQ is not a compounding-pharmacy-accessible substance and is not an FDA-approved therapy, the safety discussion is primarily about what physicians should tell patients asking about it, rather than about clinical monitoring parameters for active therapy