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Conjugates of catecholamines with cysteine and GSH in Parkinsons disease: Possible mechanisms of formation involving reactive oxygen species

Molecular Pharmaceutics, 18 (3) acs.molpharmaceut.0c00946, 940-951

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117 Clinical studies have shown that, although combination therapy with resveratrol does not present obvious side effects and is generally well tolerated, a double-blind trial demonstrated an increase in fat mass and a decrease in lean body mass after 3 months (p = 0.03 and 0.004), 116 and previous research indicates that high-dose resveratrol treatment may be associated with elevated TSH levels and an increased risk of thyroid enlargement

Symptomatic improvement often precedes laboratory normalisation

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