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The depletion of Grk2 expression in aortic smooth muscle cells also impairs the proliferative effect of endothelin and Ang II [57], that should prevent the increase in blood pressure

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For example, the catalytic activity of the native enzyme dramatically reduces when the Sec residue in the type I ID enzyme was replaced by a cysteine (Cys) moiety 64,65

One study demonstrated that human iPSCs could be differentiated into notochordal cell-like cells when cultured in the presence of natural NP tissue matrix (Liu et al., 2014

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These caspases cleave GSDMD, releasing its N-terminal fragment