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In addition, exogenous IGF-1 administration has been shown to reduce serum glucose levels [95, 143, 144], not only in healthy individuals [140, 145147], but also in those with insulin resistance [148, 149], type I [150152], and T2D [153155]

What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

Oral versions such as capsules or troches are more convenient, but absorption through the digestive tract is far less consistent, so the amount that actually reaches circulation can vary widely

Ishida, J., et al

What If: 5-Amino-1MQ Dosage Scenarios What If I Accidentally Inject Air Into the Vial During Reconstitution