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observed that the association of vitamin B 12 deficiency along with the concomitant use of metformin and proton pump inhibitors was significantly greater than those on monotherapy

Concurrently, it disrupts the PI3K/Akt/mTOR cascade, balancing the interplay between apoptosis and protective autophagy, which often culminates in synergistic cell death in resistant cancer models [33, 42]

This prevents bias when scientists evaluate outcomes and improves the reliability of the trials results

Time -3: = 0.009, t (107) = 0.57, p = 0.57) (Fig

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