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Key Takeaways Studied in over 20 clinical trials with about 2,000 adults total Standard daily dose runs from 1,000 to 3,000 mg of pure MSM Reduces osteoarthritis pain scores by 25% at 12 weeks of use Reduces post-exercise muscle soreness by 17% in active adult athletes Pairs well with glucosamine and chondroitin in many 3-in-1 formulas Excellent safety profile across 20-plus trials at 12 to 26 weeks What Is MSM

10.1016/S1097-2765(00)80425-6 133

Science 334 , 12781283 (2011)

3 It is important to note that the conversion of substances from a more lipophilic state to a more hydrophilic state often results in the production of reactive intermediates, which can be more toxic than the original substance

Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial

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