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Both are backed by decades of research

n = 7, sg Fbxw7 -2

Assessment of amyloid in pathologically confirmed frontotemporal dementia syndromes

Validation Data Gallery V5-Trap Magnetic Agarose for immunoprecipitation of V5-tagged proteins

Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brning U, et al

For example, increased Rac1 activity, either through KO/knockdown of Rac1 upstream GAP proteins such as alpha-chimaerin and BCR/ABR, or the expression of constitutively active Rac1 mutants, led to unstable theta-burst stimulation (TBS)-induced LTP that gradually decayed to the baseline response at the CA1 synapse (Oh et al., 2010