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GLUTATHIONE AS AN ANTIOXIDANT Oxygen radical stress occurs in all aerobic organisms as a result of aerobic metabolism, with intermediates such as superoxide and hydrogen peroxide that lead to further production of oxygen radicals, which can cause lipid peroxidation and disrupt metabolic processes

A dual-targeting strategy focused on lactate metabolism and lactylation regulatory enzymes offers the potential to simultaneously address immunosuppression and drug resistance, establishing a novel method for precision lactylation intervention

What makes glutathione so important is that it plays a key function in helping to protect the immune system and seemingly provides the body with a layer of protection against foreign pathogens that can destroy or mutate healthy cells

aeruginosa biofilms (Vitko et al., 2016

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The convergence of synaptic dysfunction, mitochondrial failure, neuroinflammation, and impaired protein clearance underscores the complexity of the disease and the need for early, multi-mechanistic neuroprotective interventions