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Blood 106(9):3150-3159, 2005

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Figure 2 6 Conclusion It is obvious that not all Cys residues are the same and that the Cys residues that confer signaling properties to proteins are unique because of their position in the protein, the surrounding amino acids, protein cellular localization, and its redox environment

(Bravo and Anacona, 2001

Without previous testing in humans to assess its safety and potential efficacy (powered to detect a CSD), we relied on published research and studies which used 11 participants (77) and 40 participants (74, 78), and estimated that a sample size of 30 participants would be adequate for statistical analysis

By modulating these inflammatory signalling pathways, Nrf2 can regulate the production of inflammatory factors and dampen the cellular inflammatory response, thereby combatting the progression of arthritis