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A 2010 study using the Broad Institute's Connectivity Map database found that GHK-Cu at physiologic doses modulated approximately 31% of the 16,000+ human genes evaluated, shifting gene expression toward a more youthful pattern

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Acetylation of cGAS by KAT5 in its N-terminal domain promotes its DNA-binding ability, increasing the transcription of downstream antiviral genes

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Its presence seems to disrupt AR and FOXA1 signaling [66]

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Wang J, Shanmugam A, Markand S, Zorrilla E, Ganapathy V, Smith SB

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