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The GLP-1 metabolite GLP-1(9-36) amide enhanced human aortic EC viability in response to hypoxic injury and hydrogen peroxide treatment via a NO- and mitochondria-dependent mechanism (187)

But in animals fed a high-fat diet, mast cell inhibitors stopped the inflammation, histamine release, and weight gain

2024;357 doi: 10.1002/ardp.202400061

Activation of these receptors by nonanal and citronellal leads to a decrease in serotonin levels within PNECs and the release of the neuropeptide calcitonin gene-related peptide (CGRP)