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Generally, most GSTs are upregulated rather than downregulated during the resistance reaction, as confirmed in pepper leaves infected with Obuda pepper virus ObPV ( Arabidopsis thaliana (Sun et al., 2016), Beta vulgaris and beet necrotic yellow vein virus-BNYVV interactions ( - CGMMV (Satoh et al., 2013)

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However, the specific mechanism of action is still unclear and needs to be further explored

carboplatin may be used in place of cisplatin in some cases, although available evidence suggests that cisplatin may be somewhat more effective (NCI 2014b)

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