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It also stimulates fibroblast proliferation in connective tissue, increasing collagen synthesis and improving the structural quality of the repair

Tanner 2009 )

2012 Oct 19;4:149-55

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A robust link between higher LCIG doses and reduced B12 levels in PwPD with PN has been pointed out with beneficial effect of vitamin B supplementation

Altered tropomyosin expression or function could therefore amplify pro-fibrotic mechanotransduction pathways, creating a vicious cycle of increasing stiffness and fibroblast activation