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In addition, it also helps block the deposition of fats in visceral and peripheral organs

It stimulates the synthesis of key ECM components, including collagen I and III, elastin, and various glycosaminoglycans (GAGs), by signaling through pathways such as the TGF-/SMAD cascade

This approach mirrors how anti-obesity medications are used in clinical practice, where long-term maintenance therapy prevents weight regain

Semaglutide has become very popular because clinical studies show it can lead to about 15% body weight loss on average

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