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Instead, treatments are designed to: Address hyperpigmentation and patchy tone Improve texture, clarity and radiance Treat melasma, sun damage and acne marks Support long-term skin function and barrier health For a medically grounded overview of pigmentation and how it is commonly approached in dermatology, you can refer to trusted international resources such as the Cleveland Clinics guide on hyperpigmentation

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Twenty-four (69%) patients died and among them 4 had a fatal rejection

Then, for the other ones, I think you could posit some relevance

Retrieved January 21, 2014