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251,252,253 Thus, NAD(P) + /NAD(P)H acts as an important modulator of cellular energetic status, enabling the reset of redox rhythmic and transcriptional oscillations based on metabolic signals

This is suggestive of a prolonged formation of catechin via gut microbial degradation of procyanidins in the colon (Figure 3)

The consistent involvement of residues like VAL A:135 and ASN A:64 across multiple compounds suggests their critical role in the binding mechanism

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