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It is very likely, therefore, that HIF-1's oxygen responsiveness resides over a permissive range of antioxidant buffering capacities, with the demonstration that the antioxidant/pro-oxidant equilibrium effectively uncouples HIF-1 activity from the normal pattern observed in response to variations in p O 2 in the alveolar epithelium [13, 14, 82]

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However, high levels of IGFBP-3 in breast tumor tissues are associated with increased xenograft growth in mice and poor prognosis

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Cell Stem Cell 18 (6), 827838 (2016)

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1 Introduction Chronic kidney disease (CKD) represents a progressive disorder marked by ongoing kidney damage or a diminished glomerular filtration rate that persists for more than 3 months ( According to the Kidney Disease Improving Global Outcomes (KDIGO) guidelines, CKD-MBD is a systemic syndrome characterized by abnormalities in bone histology and ectopic calcification

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Circular dichroism (CD) CD spectra of Zn(II)-loaded MT2 were recorded using a J-1500 Jasco spectropolarimeter (JASCO) at 25 C in a 2 mm quartz cuvette under a constant nitrogen flow over the range of 200300 nm with a 200 nmmin 1 speed scan

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[PubMed] Acott, T.S., M.J

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