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10.1002/hep.21384 173 ZhouY.WuR.WangX.BaoX.LuC

doi: 10.1016/j.redox.2015.11.010

Sex-dependent differences in susceptibility to trichloroethylene-induced toxicity and carcinogenicity have been reported, but few studies of metabolic differences between sexes have been conducted

& He, W.-M

Recently, many other biological factors have been proposed to explain PE including genetic vulnerability 7, 8 , robust cortical representation of the pudendal nerve 9 , disturbances in central serotonergic neurotransmission 10, 11 , and thyroid diseases 12, 13

Harpagoside, one of its active constituents, exerts neuroprotective effects by modulating endoplasmic reticulummitochondria coupling (MAMs), suppressing IP3R1/GRP75/VDAC1 complex expression, and maintaining neuronal calcium homeostasis