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10.1073/pnas.0407076101 Proc Natl Acad Sci U S A

Geoditin A, an isomalabaricane triterpene compound derived from the South China Sea Sponge Geodia japonica, has been previously found to suppress melanogenesis by post-translational regulation in the endoplasmic reticulum and the degradation of TYR in the lysosome (123)