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Anesthesiology 84 , 1011 (1996)

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However, to our knowledge there have been no studies of growth factors tested in animal models with naturally occurring IVD degeneration

PMID: 26527315

Additionally, research by Du et al., 2023 demonstrated that rapamycin injection enhanced autophagy, leading to the downregulation of TFR1, which inhibited ferroptosis and reduced cognitive deficits in a Sepsis-associated encephalopathy (SAE) model in mice