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Cinnamon: Studies that supplemented type 2 diabetics and healthy individuals with cinnamon reported lower levels of fasting glucose, HbA1C, and after-meal glucose and insulin concentrations, as well as improvements in insulin sensitivity

Amijee H, Madine J, Middleton DA, Doig AJ (2009) Inhibitors of protein aggregation and toxicity

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The stated reasons included limited human safety data, immunogenicity concerns, inadequate characterization, and documented adverse events

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Symptoms : Swelling of the hands, feet, or face, fatigue, nausea, vomiting, and loss of appetite